Tumor del saco vitelino de testículo en un niño de dos años de edad con criptorquidia izquierda: reporte de un caso
Article Sidebar
Main Article Content
Abstract
Testicular cancer is a very rare malignant tumor in prepubescent males younger than 15-year-old with an incidence of 1/1 000 000. Testicular yolk sac tumor is the most common type of testicular germ cell tumor (TCGT) in children younger than 2-year-old. Clinical case: Child of 2-year-old and five months with cryptorchidism left, which presented, six months ago, progressive increase of a tumor located in the entire left groin; characterized by being of hard consistency, painless and show no discoloration changes in the overlying skin. Results: In the auxiliary examinations, the ultrasound showed: large solid mass, ovoid, heterogeneous echogenicity and multiple anemic cavities. The only tumor marker with an increase was Alpha-fetoprotein (AFP): 12 845.00 ng/mL. The presumptive diagnosis was of malignant testicular tumor until proven otherwise. Radical inguinal orchiectomy is performed with satisfactory postsurgical evolution. Conclusion: Malignant testicular tumor in prepubescent males younger than 15-year-old is very rare, and the most common type of TCGT in children younger than 2-yearold is yolk sac tumor.
Downloads
Article Details
References
Young JL, Ries LG, Silverberg E, Horm JW, Miller RW. Cancer incidence, survival, and mortality for children younger than age 15 years. Cancer. 1986; 58 (S2):598-602. https://doi.org/10.1002/1097-0142(19860715)58:2+%3C598::AID-CNCR2820581332%3E3.0.CO;2-C
Kusler KA, Poynter JN. International testicular cancer incidence rates in children, adolescents and young adults. Cancer Epidemiol. 1 de octubre de 2018; 56:106-11.DOI: 10.1016/j.canep.2018.08.002
Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Bray F, et al. International incidence of childhood cancer, 2001–10: a population-based registry study. Lancet Oncol. 1 de junio de 2017; 18(6):719-31. https://doi.org/10.1016/S1470-2045(17)30186-9
Ahmed HU, Arya M, Muneer A, Mushtaq I, Sebire NJ. Testicular and paratesticular tumours in the prepubertal population. Lancet Oncol. 1 de mayo de 2010; 11(5): 476-83. https://doi.org/10.1016/S1470-2045(10)70012-7
Thorup J, McLachlan R, Cortes D, Nation TR, Balic A, Southwell BR, et al. What is new in cryptorchidism and hypospadias—a critical review on the testicular dysgenesis hypothesis. J Pediatr Surg. 1 de octubre de 2010; 45(10):2074-8 6 . https://doi.org/10.1016/j.jpedsurg.2010.07.030
Sangüesa C, Veiga D, Llavador M, Serrano A. Testicular tumours in children: an approach to diagnosis and management with pathologic correlation. Insights Imaging. 27 de mayo de 2020; 11(1):74. https://doi.org/10.1186/s13244-020-00867-6
Williamson SR, Delahunt B, Magi Galluzzi C, Algaba F, Egevad L, Ulbright TM, et al. The World Health Organization 2016 classification of testicular germ cell tumours: a review and update from the International Society of Urological Pathology Testis Consultation Panel. Histopathology. 2017; 70(3):335-46. https://doi.org/10.1111/his.13102
Talerman A, Haije WG, Baggerman L. Serum alphafetoprotein (AFP) in patients with germ cell tumors of the gonads and extragonadal sites: Correlation between endodermal sinus (yolk sac) tumor and raised serum AFP. Cancer. 1980 ; 46(2):380-5. https://doi.org/10.1002/1097- 0142(19800715 )46:2%3C380::AID-CNCR2820460228%3E3.0.CO;2-U
Song Q-D. Ultrasound Appearances of Pediatric Testicular Yolk Sac Tumors: Twenty-one Cases in a Single Institution. J Ultrasound Med. 2018; 37(10):2457-63. https://doi.org/10.1002/jum.14597
Aso C, Enríquez G, Fité M, Torán N, Piró C, Piqueras J, et al. Gray-Scale and Color Doppler Sonography of Scrotal Disorders in Children: An Update. RadioGraphics. 1 de septiembre de 2005; 25(5):1197-214. https://doi.org/10.1148/rg.255045109
Fang C, Huang DY, Sidhu PS. Elastography of focal testicular lesions: current concepts and utility. Ultrasonography. Octubre de 2019; 38(4):302-10. https://doi.org/10.14366/usg.18062
Xu H-X, Yi X-P. Sonographic appearance of a testicular yolk sac tumor in a 2-year-old boy. J Clin Ultrasound. 2007; 35(1):55-7. https://doi.org/10.1002/jcu.20249
Teixeira RL, Rossini A, Paim NP. Tumores testiculares na infância. Rev Colégio Bras Cir. Febrero de 2009 ; 36(1):85-9. http://dx.doi.org/10.1590/S0100-69912009000100015.
Thava V, Cooper N, Egginton JA. Yolk sac tumour of the testis in childhood. Br J Radiol. 1 de d i c i embre de 1992 ; 65(780):1142-4. https://doi.org/10.1259/0007-1285-65-780-1142
Cox L, Donald JC, Machin GA, Popkin JS, Zacks D. Intraabdominal testis with yolk sac tumor in a 2-year-old child. J Pediatr Surg. 1 de agosto de 1988; 23(8):775-6. https://doi.org/10.1016/S0022-3468(88)80425-1
Ross Martin M., Morrow James W. Yolk Sac Carcinoma of the Testis. J Urol. 1 de julio de 1972; 108(1):109-11. https://doi.org/10.1097/pas.0000000000000322
Dogra VS, Gottlieb RH, Oka M, Rubens DJ. Sonography of the Scrotum. Radiology. 1 de abril de 2003; 227(1):18-36 . https://doi.org/10.1148/radiol.2271001744
Young PG, Mount BM, Foote FW, Whitmore WF. Embryonal adenocarcinoma intheprepubertaltestis. A Clinicopathologic Study of 18 Cases. Cancer. 1970; 26(5):1065-75. https://doi.org/10.1002/1097-0142(197011)26:5%3C1065::AID-CNCR2820260515%3E3.0.CO;2-K
Ultrasonography of Testicular Tumors - Abstract - European Urology 1990, Vol. 17, No. 4 - Karger Publishers [Internet]. 2021 [citado 21 de enero de 2021]. Disponible en: https://www.karger.com/Article/Abstract/464058
Arumugam D , Thandavarayan P, Chidambaram L, Boj S, Marudasalam S. Primary Nasopharngeal Yolk Sac Tumor: A Case Report. J Clin Diagn Res JCDR. Mayo de 2016; 10(5):ED06-7. DOI: 10.7860/JCDR/2016/17620.7760